With the introduction of LR 2.0 and ACR 4.5, both of these raw converters can now use camera profiles.
Here's a good article on this over at Luminous-Landscape
http://www.luminous-landscape.com/reviews/accessories/dng-profiles.shtml.
I've been playing around with the Profile Editor for a while and it offers very fine control over the colorants in a DNG file; much finer than the native sliders and curves. I was able to replace my Tungsten and Daylight ACR presets that I created from my color checker chart using Thomas For's script with a single profile that interpolates between the two color temperatures. I can now shoot under varying lighting conditions and still have good color balance using this new interpolated profile method. That was one thing I didn't like about using Thomas's script to create multiple calibration presets. I lost the interpolation that was built into the native ACR profiles (i.e. 2.4, 4.4, etc.). This forced me to create different sets of ACR presets for each color temperature calibration.
One thing to keep in mind about using these profiles: They can be embedded in the DNG, but not the XMP sidecars. I haven't tested this, but I believe if you move your proprietary raws and sidecars to a new platform, you will need to also bring along any profiles those sidecars may be referencing.
Dan